The BISAP score ( Blood urea nitrogen level > 25 mg / dL, Impaired mental status, Systemic inflammatory response syndrome, age over 60 years, pleural effusion ) has been validated as similar to other prognostic scoring systems.
22.
A high protein diet therefore produces high blood urea concentrations, and a protein-poor diet produced low blood plasma urea concentrations, without any physiological attempt to correct or mitigate these fluctuations in the level of urea in the extracellular fluids.
23.
This particular type of renal insufficiency was characterized by vasopressin-resistant high-output renal failure ( production of large volumes of poorly concentrated urine ) with a negative fluid balance, pronounced weight loss, elevation of serum sodium, chloride, osmolality and blood urea nitrogen.
24.
BUN-to-creatinine ratio ( the ratio of blood urea nitrogen to creatinine ) can indicate other problems besides those intrinsic to the kidney; for example, a urea level raised out of proportion to the creatinine may indicate a prerenal problem such as volume depletion.
25.
According to a retrospective cohort study comparing patients treated with a left ventricular assist device versus inotrope therapy while awaiting heart transplantation, the group treated with LVAD had improved clinical and metabolic function at the time of transplant with better blood pressure, sodium, blood urea nitrogen, and creatinine.
26.
High salt intake raises the blood pressure in salt sensitive individuals; lack of exercise, obesity, and high blood urea has been found in untreated people with hypertensive in comparison with people with normal blood pressure, although it is uncertain whether the former plays a causal role or is subsidiary to poor kidney function.
27.
Still, it is not certain that the symptoms currently associated with uremia are actually caused by excess urea, as one study showed that uremic symptoms were relieved by initiation of dialysis, even when urea was added to the dialysate to maintain the blood urea nitrogen level at approximately 90 mg per deciliter ( that is, approximately 32 mmol per liter ).
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