Alternatively immunohistochemical staining of a bone marrow biopsy looking for dominant plasma cell can be sought in people with a high clinical suspicion for AL amyloidosis but negative electrophoresis.
22.
If the cause for the high platelet count remains unclear, bone marrow biopsy is often undertaken, to differentiate whether the high platelet count is "'reactive "'or "'essential " '.
23.
Cancer also needed to be ruled out, so doctors did blood cell counts, a CAT scan and bone marrow biopsies, obtained through a large needle drilled through his hip.
24.
Corticosteroids are generally ineffective, though they are used to ameliorate serum sickness caused by ATG . Normally, success is judged by bone marrow biopsy 6 months after initial treatment with ATG.
25.
The definitive diagnosis is by bone marrow biopsy; normal bone marrow has 30 70 % blood stem cells, but in aplastic anemia, these cells are mostly gone and replaced by fat.
26.
The bone marrow biopsy is used both to confirm the presence of HCL and also the absence of any additional diseases, such as Splenic marginal zone lymphoma or B-cell prolymphocytic leukemia.
27.
However, since the diagnosis depends on the exclusion of other causes of a low platelet count, additional investigations ( such as a bone marrow biopsy ) may be necessary in some cases.
28.
If the cause for the low platelet count remains unclear, a bone marrow biopsy is usually recommended, to differentiate whether the low platelet count is due to decreased production or peripheral destruction.
29.
As this is relatively new and expensive technology, its adoption by physicians is not uniform, despite the advantages of comfort, simplicity, and safety for the patient when compared to a bone marrow biopsy.
30.
At Somatex Medical Technologies, which makes medical equipment like bone marrow biopsy needles in Teltow, a mile southwest of Berlin, the owner, Frank Kniep, sees the proposal as another burden on small businesses.
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