21. This destruction occurs as a result of the effect of bacterial endotoxins on bone tissue . 22. Bone metabolism can be regulated by central sympathetic outflow, since sympathetic pathways innervate bone tissue . 23. In long bones, bone tissue first appears in the diaphysis ( middle of shaft ). 24. The osteoblast cell forms new bone, while osteoclast dissolves old and worn out bone tissue . 25. _Donated bone tissue can be used in reconstructive surgery. 26. ESs have also been differentiated to natural killer ( NK ) cells and bone tissue . 27. When this condition persists, serum magnesium drops and is corrected with magnesium from bone tissue . 28. Young plesiosaurs show pachyostosis, an extreme density of the bone tissue , which might have increased relative weight. 29. Bone Tissue and Engineering Center : http : / / www . btec . cmu . edu30. One of the primary functions of : Bone tissue is to provides structural support for the body.