Smokers are especially prone to breakthrough bleeding while taking oral contraceptives; though many users experience breakthrough bleeding in the first three cycles of taking the pill, non-smokers tend to see the bleeding dissipate more quickly than smokers.
22.
A study of 118 nulliparous women treated with 5 mg / day NET for a period of 2 to 30 months found that the drug was effective in producing amenorrhea in 86 % of the women, with breakthrough bleeding occurring in the remaining 14 %.
23.
The term breakthrough bleeding or breakthrough spotting is usually used for women using hormonal contraceptives, such as IUDs or oral contraceptives, in which it refers to bleeding or spotting between any expected withdrawal bleedings, or bleeding or spotting at any time if none is expected.
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