21. This paired arrangement can also be seen in the organization of centrioles in typical animal cells. 22. CP110 is another cyclin E / CDK2 substrate which involves in centriole duplication and centrosome separation. 23. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. 24. Procentrioles assemble perpendicular to existing centrioles . 25. This discovery was made through observation after removing the pre-existing centrioles using laser microbeam. 26. Hyls1 is incorporated into centrioles as they are formed but is not required for centriole assembly. 27. Hyls1 is incorporated into centrioles as they are formed but is not required for centriole assembly. 28. Once they reach full length, the new centriole and its mother centriole form a diplosome. 29. Once they reach full length, the new centriole and its mother centriole form a diplosome. 30. By contrast, charophyte green algae and land plants ( embryophytes ) undergo open mitosis without centrioles .
