21. These complexes are then anchored at the centriole to begin formation of the centrosome . 22. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. 23. Centrosome disorientation refers to the loss of orthogonality between the mother and daughter centrioles.24. The protein appears in the study alongside seven other centrosome -associated protein candidates. 25. She discovered that the kinase PLK4 regulates the number of centrosomes an organism develops. 26. Centrosomes move to the polar regions and arrange spindle fibers for the second meiotic division.27. An important organelle in mitosis is the centrosome , the microtubule organizing center in metazoans. 28. NEDD1 recruits the ?-TuRC to the centrosome by binding to ?-tubulin. 29. During interphase, PLK1 localizes to centrosomes . 30. Failure of centrosome regulation can cause mistakes in chromosome segregation and is associated with aneuploidy.
