21. Klug was diagnosed with primary sclerosing cholangitis in 1993 and told that he eventually would need a liver transplant. 22. But it is his triumph over primary sclerosing cholangitis , or PSC, that overshadows all his other victories. 23. The 44-year-old Payton was diagnosed with primary sclerosing cholangitis , which blocks the bile ducts. 24. Changes in the extrapancreatic bile duct similar to those of primary sclerosing cholangitis ( PSC ) have been reported. 25. Autoimmune hepatitis is distinct from the other autoimmune diseases of the liver : primary biliary cirrhosis and primary sclerosing cholangitis . 26. Primary biliary cirrhosis and primary sclerosing cholangitis may require biopsy, although other diagnostic modalities have made this less necessary. 27. Payton's physician, Dr . Joseph Lagattuta, a liver specialist, said that Payton has primary sclerosing cholangitis . 28. Doctors say the disease, primary sclerosing cholangitis , is incurable and usually proves fatal within two years without a transplant. 29. LeDoux, 51, has been diagnosed with primary sclerosing cholangitis , which blocks the bile ducts and leads to cirrhosis. 30. Rarely, the bile ducts are deprived of blood, leading to severe cholangitis ( inflammation of the bile ducts ).