21. This enzyme participates in chondroitin sulfate biosynthesis and glycan structures-biosynthesis 1. 22. Others studying glucosamine and chondroitin are also trying to temper the growing public enthusiasm. 23. Little controlled research has been done on chondroitin sulfate, another popular arthritis treatment. 24. Chondroitin sulfate chains are linked to hydroxyl groups on serine residues of certain proteins.25. It also cleaves chondroitin sulfate, heparan sulfate and proteoglycans of the basal membrane. 26. This enzyme is also called "'chondroitin glucuronyltransferase II " '. 27. Suggested Dose : 500 mg of glucosamine and 400 mg of chondroitin in three doses. 28. Chondroitin seemed to be the most effective.29. Chondroitin sulfate readily interacts with proteins in the extracellular matrix due to its negative charges.30. It consists of a mixture of heparan sulfate, dermatan sulfate, and chondroitin sulfate.