21. The Centers for Disease Control and Prevention estimates 1.25 million Americans have chronic hepatitis B infections. 22. Cirrhosis has been reported to develop in 20 50 % of patients with chronic hepatitis C. 23. There is a lot of chronic hepatitis out there that cannot be explained by current tests, 24. Chronic hepatitis C afflicts nearly 4 million Americans, and worldwide, as many as 60 million people.25. Chronic hepatitis B affects 1.2 million Americans.26. Over time, a large number of people with chronic hepatitis B develop liver failure and liver cancer. 27. It is estimated that people with chronic hepatitis B die prematurely about 25 percent of the time. 28. People infected with chronic hepatitis C tend to be frequent users of the health care system globally. 29. The vast majority of people with chronic hepatitis C carry the virus indefinitely, apparently with few ill effects. 30. Four million Americans are estimated to have chronic hepatitis C, and 10, 000 die from it each year.