Cistron's chairman and CEO, Dr . Henry Grausz, said his company holds a strong position in IL-1 and, with the settlement award, " looks forward to exploiting Cistron's potential ."
22.
The Cistron-Immunex dispute serves as a signal, Elman said, that scientists and journal editors should draw up explicit confidentiality papers to " put in the file, so that what everybody has previously understood to be the case is in fact documented ."
23.
Cistron accused Dr . Steven Gillis, one of Immunex's founders, of taking confidential information from an unpublished manuscript he had been asked to review and giving it to a colleague who used it as a road map in Immunex's own efforts to clone IL-1.
24.
:( ec ) I found a rather cute write-up at a quirky site . First it points out the obvious : an ommatidium contains only about 8 rhabdomeres ( photoreceptor cells-see [ http : / / cistron . ca / ommatidia . shtml here for the fruit fly example ).
25.
"The notion of the cistron [ . . . ] must be replaced by that of a transcription unit containing regions which will be lost from the mature messenger-which I suggest we call introns ( for intragenic regions )-alternating with regions which will be expressed-exons . " ( Gilbert 1978)
26.
The dispute involved what the plaintiff, Cistron Biotechnology of Pine Brook, N . J ., called " one of the major discoveries of the emerging biotechnology industry " _ the blueprint for a human immune-system molecule known as IL-1 with potential value in treating arthritis, allergies and wounds.
27.
One of the 20-odd volumes of documents filed in the case includes a statement Cistron solicited from Edmond Fischer, University of Washington professor emeritus of biochemistry and 1992 Nobel Prize winner, that it was " reprehensible " that Gillis didn't disqualify himself from reviewing a paper about research so close to Immunex's own.
28.
It is based on the fact that mitochondrial DNA ( mtDNA ) or some parts of the ribosomal DNA cistron have relatively fast mutation rates, which give significant variation in sequences between species . mtDNA methods are only possible in eukaryotes ( as prokaryotes lack mitochondria ), whereas MLST, although initially developed for prokaryotes, is now finding application in eukaryotes and in principle could be applied to any kingdom.
29.
Cistron, based in Pine Brook, N . J ., alleged that Immunex co-founder Dr . Steven Gillis had taken confidential information from a scientific paper he had been asked to review for the British journal Nature _ and which he had recommended not be published _ and shared it with Immunex researchers pursuing the same goal, the cloning of a human immune system molecule known as IL-1 that was thought to have great therapeutic potential.
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