21. Corticosterone is converted to aldosterone by aldosterone synthase, found only in the mitochondria of glomerulosa cells.22. Rats that have been prenatally stressed have elevated basal levels and abnormal circadian rhythm of corticosterone as adults. 23. It also catalyzes the conversion of 11-deoxycorticosterone ( DOC ) to corticosterone in the mineralocorticoid pathway. 24. Exposure to tourism affects marine iguanas, and corticosterone levels can predict their survival during El Ni�o events. 25. In experiments allowing newts to be exposed to nonylphenol, there was a decrease in corticosterone and aldosterone. 26. In addition, the enzyme reduces and inactivates 17-deoxycorticosterone, the precursor of aldosterone and corticosterone . 27. Blood levels of steroid hormones like corticosterone generally increase in times of stress, like famine or bad weather. 28. As well it shows that the different brain regions differentially activate corticosterone , a hormone related to memory effects. 29. :corticosterone + reduced adrenal ferredoxin + O 2 \ rightleftharpoons 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H 2 O 30. Also, other studies show levels of stress hormones such as corticosterone rise dramatically in these birds during and after a migration.
