21. About one third respond to Dapsone . 22. Agranulocytosis occurs rarely when dapsone is used alone but more frequently in combination regimens for malaria prophylaxis. 23. Jaundice may also occur as part of the dapsone reaction or dapsone syndrome ( see below ). 24. Jaundice may also occur as part of the dapsone reaction or dapsone syndrome ( see below ). 25. However, the efficacy of oral dapsone as prevention has not been demonstrated very clearly until now. 26. Dapsone and rebamipide have been shown, in small studies, to have beneficial results for mucocutaneous lesions.27. A multidrug therapy _ consisting of three drugs ( dapsone , rifampicin and clofazimine ) _ kills the pathogen. 28. When used topically, dapsone can cause mild skin irritation, redness, dry skin, burning and itching. 29. The drug is given as an alternative to people who can not tolerate the effects of dapsone for tuberculosis. 30. Dapsone , an antibiotic, is commonly used in the United States and Brazil for the treatment of necrosis.
