21. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase . 22. The primary enzyme in the malate-aspartate shuttle is malate dehydrogenase . 23. Phosphoglycerate dehydrogenase is regulated by the concentration of serine in the cell. 24. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. 25. Homoserine dehydrogenase reduction of aspartate beta-semialdehyde into homoserine. 26. Lactaldehyde is then oxidized to lactic acid by aldehyde dehydrogenase . 27. Lactate dehydrogenase catalyzes the interconversion of pyruvate and NAD +. 28. Lactate dehydrogenase is composed of four subunits ( tetramer ). 29. This protein belongs to the aldehyde dehydrogenase family of proteins. 30. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.