Dominant inheritance means most families with CTLA4 mutations have affected relatives in each generation on the side of the family with the mutation.
22.
Mutations in EOGT are found in AOS with autosomal recessive inheritance; the other three genes account for cases with autosomal dominant inheritance.
23.
Dominant inheritance occurs when an abnormal gene from one parent causes disease even though the matching gene from the other parent is normal.
24.
In LFS, X-linked dominant inheritance was suspected, as boy and girl siblings in one family both exhibited the disorder.
25.
This type has an autosomal recessive inheritance pattern, whereas the most common subtype of Kostmann syndrome, SCN1, shows autosomal dominant inheritance.
26.
During the rediscovery of Mendelian inheritance at the turn of the 20th century, HD was used tentatively as an example of autosomal dominant inheritance.
27.
Dominant inheritance means an abnormal gene from one parent is capable of causing disease, even though the matching gene from the other parent is normal.
28.
In autosomal dominant inheritance, having only one mutated copy of the disease-causing gene in each cell is sufficient to cause signs and symptoms of the condition.
29.
In the majority of cases of M�bius syndrome in which autosomal dominant inheritance is suspected, sixth and seventh cranial nerve paralysis ( palsy ) occurs without associated limb abnormalities.
30.
However, the inheritance pattern of PRPF31 mutations is atypical of dominant inheritance, showing the phenomenon of partial penetrance, whereby a dominant mutations appear to " skip " generations.
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