In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response.
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In toxicology, hormesis is a dose response phenomenon characterized by a low dose stimulation, high dose inhibition, resulting in either a J-shaped or an inverted U-shaped dose response.
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In the case of estimation of stochastic effects, assuming a linear dose response, this averaging out should make no difference as the total energy imparted remains the same.
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Even though exercise as carried out in the general population has only modest effects, a dose response curve is found, and very intense exercise can lead to substantial weight loss.
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Rivaroxaban has predictable pharmacokinetics across a wide spectrum of patients ( age, gender, weight, race ) and has a flat dose response across an eightfold dose range ( 5 40 mg ).
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In Ames test, where the varying concentrations of the chemical are used in the test, the dose response curve obtained is nearly always linear, suggesting that there is no threshold for mutagenesis.
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In studies comparing the effectiveness of olopatadine to alcaftadine, there was not a dose response increase of adverse effects as alcaftadine doses increases for 0.05 % to 0.1 % to 0.25 %.
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This success was made possible by the integration of Animas'predictive hypoglycemia-minimizing algorithm and Dexcom's G4 PLATINUM CGM . The Animas Vibe varied in insulin dosing response dependent upon an " aggressiveness factor ".
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Alternative definition : ED95 ( when referring to non depolarising muscle relaxants ) is the ED50 from a cumulative log dose response curve where the quantum is a 95 % reduction in twitch height
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Because this approach requires establishment of cause and effect in epidemiological studies and a thorough understanding of human dose response, data to support these types of action levels exist for only a few environmental chemicals.
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