21. Bulimia patients may need to manage edema , hypokalemia or esophagitis. 22. A thickened left ventricle in his heart is causing pulmonary edema . 23. In severe cases, high-altitude cerebral edema results in death. 24. The other components are called edema factor and lethal factor. 25. These toxins cause death and tissue swelling ( edema ), respectively. 26. Resultant hypoproteinemia may be severe enough to cause generalized edema . 27. In rare cases, a Parvovirus B19 infection may cause generalized edemas . 28. The physiological cause of altitude-induced edema is not conclusively established. 29. Females also report more physical discomfort due to Reinke's edema . 30. This reduces extravasates ) into the surrounding soft tissue, causing edema .