21. The use of effective dose enables comparisons of overall dose received regardless of the extent of body irradiation. 22. It is related to the gray by weighting factors described in the articles on equivalent dose and effective dose . 23. If only part of the body is irradiated, then only those regions are used to calculate the effective dose . 24. Another 2, 572 women took two tablets a day because the scientists were uncertain of the most effective dose . 25. The effective dose in humans is very uncertain . talk ) 14 : 24, 17 August 2009 ( UTC) 26. The trial will also seek to answer three questions : What is the most effective dose level for Endostatin? 27. Zinc supplementation may reduce the minimum effective dose of amphetamine when it is used for the treatment of ADHD. 28. Furthermore, breast feeding is possible but only if lowest effective dose is used and neonatal development is closely monitored. 29. "Treatment should be based on controlling symptoms, and using the lowest effective dose that controls symptoms, " said Szefler. 30. Sometimes side effects appear even at a minimal clinically effective dose , leading the physician to search for a different drug.