21. Of these compounds, atranorin showed the highest inhibition of proteolytic enzymes trypsin and porcine pancreatic elastase . 22. The first isozyme, pancreatic elastase 1, was initially thought to be expressed in the pancreas. 23. In fact, pancreatic elastase is expressed in basal layers of epidermis ( at protein level ). 24. Neutrophil elastase is an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. 25. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A. 26. Clinical literature that describes human elastase 1 activity in the pancreas is actually referring to elastase 2A. 27. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. 28. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. 29. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. 30. The researchers injected elastase , an enzyme that breaks down elastin, into the wind pipes of rats.