21. A manganese porphyrin catalyst developed by Nolte et al . capable of successive epoxidation of alkene polymer. 22. Titanium isopropoxide is a component of the Sharpless epoxidation , a method for the synthesis of chiral epoxides. 23. When alkene 2 undergoes epoxidation with m-chloroperbenzoic acid ( MCPBA ), epoxide 3 is formed. 24. Figure 11 : The general reaction scheme studied by Kagan and coworkers for the sharpless epoxidation of geraniol. 25. The epoxidation of various alkanes in the presence of benzonitrile yields oxiranes in yields of 79 to 96 %. 26. Anhydrous hydrogen chloride reacts preferentially at the disubstituted alkene, whereas epoxidation with mCPBA occurs at the trisubstituted alkene. 27. Epoxidation of a substituted cyclohexene affords a product where the R group resides in the pseudo-equatorial position.28. These substrates are resistant to many epoxidation reagents, including oxaziridines, hydrogen peroxide, and manganese oxo compounds. 29. Eleuterio also worked on epoxidation of hexafluoropropylene, finding a practical synthesis of hexafluoropropylene oxide using hydrogen peroxide anion. 30. Fourth, the products of the Sharpless epoxidation are predictable using the Sharpless Epoxidation model discovered by Debbie van Basten.
