21. The hemoglobin is phagocytosed by macrophages, and split into its heme and globin portions. 22. Another example are the globin genes which hemoglobin F ) are paralogs of each other. 23. It is of ancient evolutionary origin, and is homologous to nerve globins of invertebrates. 24. These hubs were discovered during observation of activated alpha-and beta-globin loci. 25. This gene is highly conserved in vertebrates which is upstream from the alpha globin gene cluster. 26. The latter reaction is a remnant activity of the more ancient nitric oxide dioxygenase function of globins . 27. Structure, O 2 binding, and reduction of globins appear optimized for a NO dioxygenase function. 28. Cytoglobin is a globin molecule ubiquitously expressed in all tissues and most notably utilized in marine mammals. 29. The globin portion, a protein, is degraded into amino acids and plays no role in jaundice. 30. "Globin 2 residents "-These aliens appear to resemble ( if anything ) vampires.
