21. They are substituted by Grignard reagents to give magnesium salts and an extended alkyl compound. 22. Triethylindium can be prepared in a similar fashion but with the grignard reagent , EtMgBr. 23. In comparison to aryl chlorides and bromides, aryl fluorides form Grignard reagents only reluctantly. 24. However, with hindered Grignard reagents , the reaction may proceed by single-electron transfer. 25. Grignard reagents form similar organocopper compounds.26. Phenylmagnesium bromide is a Grignard reagent . 27. Reactions with magnesium, in contrast, must exclude water since protonolysis destroys the Grignard reagent . 28. Magnesium aryl halides are Grignard reagents , which are useful in organic synthesis of other aryl compounds. 29. For example, sulfinate esters made from sulfinyl chlorides and menthol can be used to make Grignard reagents . 30. Alkyl chlorides react with magnesium to give Grignard reagents , transforming an electrophilic compound into a nucleophilic compound.
