21. Diseases associated with this genus include : hepatitis, hepatocellular carcinomas ( chronic infections ), cirrhosis. 22. Diseases associated with this genus include : hepatitis, hepatocellular carcinoma ( chronic infections ), cirrhosis. 23. This population has a 40 % lifetime risk of death from cirrhosis or hepatocellular carcinoma . 24. Hepatocellular carcinoma cell proliferation may arise from miR-21 interaction with MAP2K3, a tumor repressor gene.25. On December 14, 2013 he died from hepatocellular carcinoma . 26. In addition to causing hepatitis, infection with HBV can lead to cirrhosis and hepatocellular carcinoma . 27. Hepcortespenlisimut-L, an oral cancer vaccine also has US FDA orphan drug designation for hepatocellular carcinoma . 28. Inhibition of miR-127 expression is linked with Hepatocellular carcinoma . 29. It is unclear if screening those with chronic liver disease for hepatocellular carcinoma improves outcomes. 30. Other cancers CLU has been implicated in include breast cancer, pancreatic cancer, hepatocellular carcinoma , and melanoma.
