21. Histidine was first isolated by German physician Albrecht Kossel and Sven Hedin in 1896.22. In the last step, L-histidinal is converted to L-histidine . 23. Just like animals and microorganisms, plants need histidine for their growth and development. 24. The virA protein has autokinase activity : it phosphorylates itself on a histidine residue. 25. Promising supplements include chromium histidine and chromium nanoparticles. 26. Imidazoleglycerol-phosphate dehydratase is an enzyme catalyzing the sixth step of histidine production. 27. It contains one histidine residue and five cysteine residues 28. A histidine is involved in the catalytic mechanism. 29. It is a secondary disorder of histidine metabolism. 30. The guanidinium groups and hydrogen on the protonated imidazole ring from the histidine residue.