Hyperkeratosis and altered epithelial thickness may be the only histologic features of a leukoplakia lesion, but some show dysplasia.
22.
An estimated 5 % of dogs may be affected by footpad hyperkeratosis, a thickening of the footpad and sometimes nose.
23.
The hyperkeratosis may grow more severe but more localized and is generally only present on flexural folds of the major joints.
24.
After a few months hyperkeratosis develops with a dark grey or brown, ridged appearance on the ankles, knees and elbows.
25.
Histological examination showed hyperkeratosis, marked papillomatosis, proliferation of capillaries in the upper dermis, and lymphectasia in the lower dermis.
26.
As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis.
27.
Presence of certain other mucosal lesions, especially those that cause hyperkeratosis and / or dysplasia, e . g ., lichen planus.
28.
Histologic examination shows uniform and pronounced hyperkeratosis, acanthosis, and papillomatosis without epidermal vacuolization, parakeratosis, or eosinophilic inclusions suggestive of viral warts.
29.
Using dermoscopy, dermatologists found point-like hemorrhages and onycholysis ( letting go of the nail ) in a patient who presented with hyperkeratosis.
30.
People with the other type, NPS-type, do not have extensive palmoplantar hyperkeratosis but do have hyperkeratosis on other areas of the body.
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