21. Mutations in MYL2 have been associated with familial hypertrophic cardiomyopathy ( FHC ). 22. The lake is hypertrophic , leading to eutrophication with corresponding poor water quality. 23. Following further testing, Naumoff was diagnosed with hypertrophic cardiomyopathy ( HCM ). 24. She scans medical Web sites about hypertrophic cardiomyopathy. 25. About one in 500 people have hypertrophic cardiomyopathy. 26. The breed does have instances of the genetic disorder hypertrophic cardiomyopathy ( HCM ). 27. Hypertrophic cardiomyopathy involves enlargement and " thickening " of the heart muscle.28. Chondrocytes undergo terminal differentiation when they become hypertrophic , which happens during endochondral ossification. 29. Hypertrophic cardiomyopathy ( HCM ) is a health concern in many pure breed cats.30. Developmental orthopedic diseases include panosteitis and hypertrophic osteodystrophy.