21. Together the two transcription factors allow the RNA pol I complex to bind with the polymerase I initiation factor , Rrn3. 22. Eukaryotic translation initiation factor 4 gamma has been shown to interact with MKNK1, EIF4A1, EIF4E, MKNK2 and PABPC1. 23. This domain is also found in other proteins such as translation initiation factor IF-2 and tetracycline-resistance proteins. 24. The only known protein containing hypusine is eukaryotic translation initiation factor 5A ( eIF5A ) and a similar protein found in archaebacteria. 25. Just like XPB, XPD is also a part of human transcriptional initiation factor TFIIH and has ATP-dependent helicase activity. 26. Binding of ATP allows for dimerization, which subsequently brings the initiation factor and ribosomal subunit in close enough contact to associate. 27. In order to bind promoters, RNAP core associates with the transcription initiation factor sigma ( ? ) to form RNA polymerase holoenzyme. 28. Translational GTPases involved in protein biosynthesis are also affected by ppGpp, with Initiation Factor 2 ( IF2 ) being the main target. 29. Subsequently, it cleaves host cell initiation factor eIF-4G at bonds-Gly-Arg-and-Lys-Arg- 30. The cytosolic isoform of eukaryotes'Poly ( A ) binding protein binds to the initiation factor eIF4G via its C-terminal domain.
