The bowel is occasionally insufflated with air to maximize visibility ( a procedure which gives one the false sensation of needing to take a bowel movement ).
22.
Because of its volume, it s likely to be impossible to insufflate the 25 grams of beans required to reach the active dose of DMT present in the beans.
23.
At up to 0.16 % ( 1.6 mg per gram ) DMT, an effective 40 mg dose of insufflated DMT would require 25 grams or more.
24.
That chart shows that for ketamine, injection ( either intramuscularly or intravenously ) is the most efficient, and insufflating is substantially less efficient ( requires three halves the amount ).
25.
It has been documented that the threshold dose in some individuals is as much as 10 mg insufflated requiring over 24 grams of beans for an effective dose of 5-MeO-DMT.
26.
Smoking freebase cocaine has the additional effect of releasing methylecgonidine into the user's system due to the pyrolysis of the substance ( a side effect which insufflating or injecting powder cocaine does not create ).
27.
"' European "'( dry ) snuff is intended to be shallowly " sniffed " ( technically insufflated ) into the nose, where nicotine is absorbed through the mucous membranes in the nostrils.
28.
The cocaine typically is poured onto a flat, hard surface ( such as a mirror, CD case or book ) and divided into " bumps ", " lines " or " rails ", and then insufflated.
29.
At up to 0.04 % ( 0.4 mg per gram ) 5-MeO-DMT, an effective light 5 mg dose of insufflated 5-MeO-DMT would require over 12 grams of beans.
30.
Of the 2C-T family, there have been a few confirmed deaths due to 2C-T-7, which involved either insufflating large ( > 30 mg ) doses and in one case an unknown oral dose was combined with 200 mg MDMA.
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