21. However, bog spavin can be a sign that the horse has joint disease , which is a very significant finding. 22. OSTEOARTHRITIS, or degenerative joint disease . 23. Nearly 21 million Americans suffer osteoarthritis, the form of the joint disease typically caused by the wear-and-tear of aging. 24. It is worsened with time, becoming irreversible . This is the etiology of degenerative joint disease . ( 5) 25. Persistent knee pain blamed on arthrosis, a degenerative joint disease , has forced the pope to cancel several public appearances recently. 26. Raynaud's phenomenon is the initial symptom that presents for 70 % of patients with scleroderma, a skin and joint disease . 27. Osteoarthritis Update Osteoarthritis is the most common form of joint disease in the world, affecting every race and ethnic group. 28. Osteoarthritis is a painful degenerative joint disease that affects the knees, hips, back and the small joints in the fingers. 29. Learn more about temporomandibular joint disease ( or TMJ ) at this site hosted by the TMJ Association Ltd .. 30. Margrethe, who is known for being energetic, has a degenerative joint disease found chiefly in elderly people in both knees.