Shortly after infection, the immune adaptive response is induced by dendritic cells ( Langerhans cells ) present in the CLA molecule.
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These Langerhans cells are antigen-presenting cells, which pick up pieces of invading pathogens and use them to elicit an immune response.
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TSLP-activated Langerhans cells of the epidermis induce the production of pro-inflammatory cytokines like TNF-alpha by T cells potentially causing atopic dermatitis.
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This provided a means to stimulate robust immune responses safely as the skin patch-based immunization targeted Langerhans cells in the skin.
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The main type of cells which make up the epidermis are Merkel cells, keratinocytes, with melanocytes and Langerhans cells also present.
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CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages.
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Patients with Langerhans Cell Histiocytosis, often called LCH, have too many histiocytes, a form of white blood cell, growing in their bodies.
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In the skin, keratinocytes, fibroblasts and Langerhans cells take up and express antigens and are responsible for inducing a primary antibody response.
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"Skin " : In normal epidermis, koebnerisin ( S100A15 ) is expressed by epidermal basal and differentiated keratinocytes, melanocytes, and Langerhans cells.
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Your reference for Langerhans cells in reptiles is a good one, though .-- talk ) 00 : 15, 23 May 2009 ( UTC)
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