21. Recently, additional inhibin specific binding proteins were identified in inhibin target tissues, including pituitary and Leydig cells . 22. This may be related to the damaged Leydig cells , as a result of the decreasing of inhibin expression. 23. Leydig cell hypoplasia does not occur in biological females as they do not have either Leydig cells or testicles.24. Leydig cell hypoplasia does not occur in biological females as they do not have either Leydig cells or testicles. 25. In the male reproductive system the NR4A1 gene is a promoter of insulin-like 3 in Leydig cells . 26. They are large enough to be seen in an optical microscope and can be visualized using Leydig cell tumours. 27. For men it acts in the same way as LH; stimulating the Leydig cells in the testes to produce testosterone. 28. They have been shown to secrete 25-hydroxycholesterol, a sterol that can be converted to testosterone by Leydig cells . 29. In situ ligand binding studies have shown that 125 I inhibin ?A binds specifically to Leydig cells throughout rat testis development. 30. Cells called the Leydig cells lie between the tubules; these produce hormones called androgens; these consist of testosterone and inhibin.
