21. Each chloride channel can be closed by only one ligand molecule. 22. The mammalian TSPO in a complex with diagnostic ligand is nomomeric. 23. The total concentrations of receptor and ligand in the system are constant 24. They can also bind to various ligands for different biological purposes. 25. They are used as ligands in homogeneous catalysis and coordination chemistry. 26. However, natural GDNF ligands are of a limited clinical use. 27. Both MPRs share 4 residues that are essential for ligand binding. 28. PMI is monomeric and metallodependent on Zinc as a cofactor ligand . 29. LGIC receptor ligands are valuable to investigate their structure and function. 30. FGFR1 activity also displays focal dependence in terms of ligand signaling.
