The Rockefeller team is already working on lysins from viruses that attack cholera and Yersinia pestis, the agent of plague.
22.
A virus called gamma phage replicates inside the anthrax bacterium and breaks out with the help of an enzyme called lysin.
23.
Phage lytic enzymes ( lysins ) produced during bacteriophage infection are responsible for the ability of these viruses to lyse bacterial cells.
24.
Lysins could thus provide a whole new class of antibiotics, in his view, and one to which bacteria could not develop resistance.
25.
The scientists have also made lysin the basis of a handheld sensor that detects whether anthrax spores are in the environment . _ NICHOLAS WADE
26.
In these crystal structures, the PSI domain takes on a closed tertiary structure similar to that of NK-lysin and saposin.
27.
For bacteriophage to survive they need to replicate inside a bacterial cell and release their progeny phage when they are assembled using their lysin.
28.
If injected quickly enough, the lysin would destroy the anthrax bacteria in the bloodstream before they had multiplied and released overwhelming amounts of toxin.
29.
An important feature of the lysin is that it attacks only anthrax and a rare strain of a closely related bacterium, the scientists say.
30.
Despite a similarity in the overall fold, the variation in the surface features of SP18 and lysin account for their different roles in fertilization.
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