21. These vacuoles are therefore seen as fulfilling the role of the animal lysosome . 22. Damaged proteins and lipids accumulate in lysosomes as lipofuscin. 23. These enzymes are released into the compartment by lysosomes . 24. The autophagosome eventually fuses with lysosomes and the contents are degraded and recycled. 25. Most of the members become activated at the low pH found in lysosomes . 26. The osteoclasts are multi-nucleated cells that contain numerous mitochondria and lysosomes . 27. Membrane fusion of the phagosome and lysosome is regulated by Rab 5 protein. 28. Macrophages possess a repertoire of antimicrobial molecules packaged within their granules and lysosomes . 29. The PINK1 / parkin pathway then designates the mitochondria for degradation by lysosomes . 30. Lysosomes are cell organelles found in most animal cells.
