The phage genes expressed in this dormant state code for proteins that repress expression of other phage genes ( such as the structural and lysis genes ) in order to prevent entry into the lytic cycle.
22.
During reactivation from latency, the herpes simplex virus ( HSV ) enters its lytic cycle, and uses anterograde transport mechanisms to migrate from dorsal root ganglia neurons to the skin or mucosa that it subsequently affects.
23.
The distinction between lysogenic and lytic cycles is that the spread of the viral DNA occurs through the usual prokaryotic reproduction, while the lytic phage is spread through the production of thousands of individual phages capable of surviving and infecting other cells.
24.
If bacteriophages undertake the lytic cycle of infection upon entering a bacterium, the virus will take control of the cell s machinery for use in replicating its own viral DNA . If by chance bacterial chromosomal DNA is inserted into the viral capsid which is usually used to encapsulate the viral DNA, the mistake will lead to " generalized transduction ".
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