Because of the need for a multi-part protein-system, microsomes are necessary to analyze the metabolic activity of CYPs.
22.
In tests with liver microsomes, dealkylation seemed to be mediated by CYP3A4, but other CYP enzymes appear to be involved as well.
23.
Regucalcin is expressed in the neuron of brain tissues, and the decrease of brain regucalcin causes accumulation of calcium in the brain microsomes.
24.
These functions include the synthesis of collagen, carnitine, and neurotransmitters; the synthesis and catabolism of tyrosine; and the metabolism of microsome.
25.
Preparative rotors are used in biology for pelleting of fine particulate fractions, such as cellular organelles ( mitochondria, microsomes, ribosomes ) and viruses.
26.
These proteins are the Sec62 proteins, believed to be associated with the Sec61 and Sec63 constituents of the general protein secretory systems of yeast microsomes.
27.
He also discovered cytoplasmic granules full of RNA and named them " microsomes ", which were later renamed ribosomes, the protein synthesizing machineries of cell.
28.
To get microsomes containing a specific CYP or for high amounts of active enzyme, microsomes are prepared from Sf9 insect cells or in yeast via heterologous expression.
29.
To get microsomes containing a specific CYP or for high amounts of active enzyme, microsomes are prepared from Sf9 insect cells or in yeast via heterologous expression.
30.
It was also found that ( " S " )-styrene oxide was preferentially hydrolyzed than the " R " enantiomer in human liver microsomes.
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