Other compounds like 1, 25-dihydroxyvitamin D 3, 12-O-tetradecanoylphorbol-13-acetate ( TPA ) and GM-CSF can induce HL-60 to differentiate to monocytic, macrophage-like and eosinophil phenotypes, respectively.
22.
The criteria for an acute myeloid leukemia case to fall under the M2 subtype is the following : 20 % + nonerythroid cells in peripheral blood or bone marrow are myeloblasts; monocytic precursors are < 20 % in bone marrow and granulocytes are 10 % + of cells ( Mihova, 2013 ).
23.
However, the term " histiocyte " has been used for multiple purposes in the past, and some cells called " histocytes " do not appear to derive from monocytic-macrophage lines . ( The term Histiocyte can also simply refer to a cell from monocyte origin outside the blood system, such as in a tissue ( as in rheumatoid arthritis as palisading histiocytes surrounding fibrinoid necrosis of rheumatoid nodules ).
24.
The primary vectors for " Borrelia burgdorferi " are the deer tick " Ixodes scapularis " in Eastern parts of the United States, " Ixodes pacificus " in California and Oregon, and " Ixodes ricinus " in Europe . " Dermacentor variabilis " may also carry " Anaplasma phagocytophilum ", the causative agent of HGE ( human granulocytic ehrlichiosis ), and " Ehrlichia chaffeensis ", the causative agent of HME ( human monocytic ehrlichiosis ).
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