Auerbach's plexus, also known as the myenteric plexus, is a collection of unmyelinated fibers and postganglionic autonomic cell bodies that lie between the circular and longitudinal layers of the muscularis externa in the gastrointestinal tract.
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In achalasia, there is idiopathic destruction of parasympathetic ganglia of the Auerbach's ( Myenteric ) plexus of the entire esophagus, which results in functional narrowing of the lower esophagus, and peristaltic failure throughout its length.
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Both command neurons and interneurons are spread throughout two layers of gut tissue called the myenteric plexus and the submuscosal plexus . ( " Solar plexus " is actually a boxing term that refers simply to nerves in the abdomen .)
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He is credited with the discovery of " Plexus myentericus Auerbachi ", or Auerbach's plexus, a layer of ganglion cells that provide control of movements of the gastro-intestinal tract, also known as the " myenteric plexus ".
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The primary effect of serotonin involves the increase in peristaltic contraction through its effects on both ENS neurons and smooth muscle . 5-HT also activates a neural secretory response, whereby binding at 5-HT1P receptors on myenteric neurons triggers a signalling cascade in the submucosal plexus.
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