21. The proteins are immunoglobulin light chains ( paraproteins ) and are produced by neoplastic plasma cells. 22. The T cells are involved in the malignancy, showing neoplastic changes with evidence of mitosis. 23. Aberrations of wnt signaling, as well as SFRPs, can contribute to the neoplastic process. 24. ERCC4 ( XPF ) is normally expressed at a high level in cell neoplastic colon epithelium. 25. Leukostasis is different from leukemic infiltration which is a neoplastic process where leukemic cells invade organs. 26. The MPE approach can be applied to not only neoplastic diseases but also non-neoplastic diseases. 27. The MPE approach can be applied to not only neoplastic diseases but also non-neoplastic diseases. 28. Additionally, laparoscopy can also diagnose metastasized cancer, as can presence of neoplastic cells on abdominocentesis. 29. Prokaryotic and eukaryotic microorganisms as well as neoplastic cells are often found to be resistant to drugs. 30. Anemia of chronic disease may also be due to neoplastic disorders and non-infectious inflammatory diseases.