21. The protein aPKC promotes self-renewal, encouraging the neuroblast to keep dividing and carry out its lineage. 22. Tumor formation occurs when TA-GMCs revert to type II neuroblasts resulting in a highly increased cellular proliferation. 23. The switch from pluripotent neuroblast to differentiated cell fate is facilitated by the proteins Prospero, Numb, and Miranda. 24. In the neuroblast phase of development ?-internexin is found in the neural tube and neural crest derived neuroblasts. 25. In the neuroblast phase of development ?-internexin is found in the neural tube and neural crest derived neuroblasts . 26. A ganglion mother cell ( GMC ) is the cell derived from the division of a neuroblast in the GMC. 27. The temporal regulation of neuroblast asymmetric division is controlled by proteins Hunchback ( Hb ) and sevenup ( svp ). 28. In " Drosophila melanogaster ", SCRIB is involved in synaptic function, neuroblast differentiation, and epithelial polarization. 29. In the neuroectoderm, small clusters of equivalent cells acquire the potential to become neuroblasts , through the expression of proneural genes. 30. Neuroblasts are the progenitor cells which divide asymmetrically to give rise to another neuroblast and a ganglion mother cell ( GMC ).