21. In May 2014, Carroll was diagnosed with stage IV pancreatic neuroendocrine cancer and liver metastasis. 22. Neuroendocrine neurons were discovered in the peripheral nervous system, regulating, for instance, digestion.23. The origins and significance of patterning in neuroendocrine secretion are still dominant themes in neuroendocrinology today. 24. The study reviled that PSMB4 mRNA was significantly associated with proliferative activity of neuroendocrine pulmonary tumors. 25. It is linked to neuroendocrine differentiation. 26. A phase II clinical trial for advanced pancreatic neuroendocrine tumors ( pNET ) has reported results. 27. SCLC derived from neuroendocrine cells may express CD56, neural cell adhesion molecule, synaptophysin or chromogranin. 28. On the other hand, its large role in the neuroendocrine system awards it the CVO classification. 29. Low-to intermediate-grade neuroendocrine carcinomas of the pancreas may be called islet cell tumors. 30. The major center of neuroendocrine integration in the body is found in the hypothalamus and the pituitary gland.
