21. Mutated p53 is also involved in the pathophysiology of leukemias, lymphomas, sarcomas, and neurogenic tumors. 22. Therefore, patients with neurogenic intermittent claudication have less disability in climbing steps, pushing carts and cycling. 23. MODY 6 arises from mutations of the gene for the transcription factor referred to as neurogenic differentiation 1. 24. Pseudoclaudication, now referred to as neurogenic claudication, typically worsen with standing or walking and improve with sitting. 25. Traumatic brain injury may cause a range of serious coincidental complications that include cardiac arrhythmias and neurogenic pulmonary edema. 26. The ability to ride a stationary bike for a prolonged period of time differentiates neurogenic claudication from vascular claudication. 27. These are controlled by motor pathways which exist somewhere between volition and the triggering of each neurogenic muscle action. 28. "' Catatonia "'is a state of neurogenic motor immobility and behavioral abnormality manifested by stupor. 29. An association with vulval cancer and urothelial carcinoma with squamous differentiation in patients with neurogenic bladder has also been noted. 30. In vertebrates, skeletal muscle contractions are neurogenic as they require synaptic input from motor neurons to produce muscle contractions.
