21. CLCF1 is closely related to other proteins called cardiotrophin-1 and ciliary neurotrophic factor. 22. There is an association of the disease with brain-derived neurotrophic factor ( BDNF ). 23. ;Neurons : G-CSF can also act on neuronal cells as a neurotrophic factor. 24. It was hypothesized that interactions between neurotrophic factors could alter the optimal concentrations of each factor. 25. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. 26. Decreased brain-derived neurotrophic factor ( BDNF ) is known to be associated with depression. 27. There are several potential biomarkers, including Brain-Derived Neurotrophic Factor and various functional MRI techniques. 28. The genetic mutation is in the gene encoding the neurotrophic tyrosine kinase receptor ( SCN9A gene ). 29. The survival factors are neurotrophic factors, including molecules such as nerve growth factor ( NGF ). 30. DA may promote neurotrophic processes in the adult hippocampus, as 5-HT and NA do.