21. These are supported by small bundles of microtubules that arise near a point on the nuclear membrane . 22. The nuclear membrane consists of two lipid bilayers the inner nuclear membrane , and the outer nuclear membrane. 23. Heterochromatin protein 1 ( HP1 ) binds both chromatin and the LBR . ONM, outer nuclear membrane . 24. The nuclear membrane consists of two lipid bilayers the inner nuclear membrane, and the outer nuclear membrane. 25. The nuclei are prominent and usually contain one or two large nucleoli, and have prominent nuclear membranes . 26. This powerful detergent is often used to break open all membranes within a cell including the nuclear membrane . 27. Prokaryotic cells lack a nuclear membrane so DNA is unbound within the cell; eukaryotic cells have nuclear membranes. 28. Prokaryotic cells lack a nuclear membrane so DNA is unbound within the cell; eukaryotic cells have nuclear membranes . 29. These proteins are embedded within the nuclear membrane at the region where the inner and outer leaflets connect. 30. Lamin A cannot be produced, and prelamin A builds up on the nuclear membrane , causing a characteristic nuclear blebbing.