21. Thus, the size of the nucleolus may be an early indicator of amyotrophic lateral sclerosis. 22. At metaphase, a proteinaceous remnant of the nucleolus often remains associated with the secondary constriction. 23. Each cell has a round shape, a large nucleolus and a small amount of cytoplasm. 24. After being produced in the nucleolus , ribosomes are exported to the cytoplasm where they translate mRNA. 25. They are located in the nucleolus and the scaRNAs ( small Cajal body-specific RNAs ). 26. The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus . 27. POLD1 / p125 has a NoDS domain that regulates transport to the nucleolus in response to acidosis. 28. Pol? structurally and functionally interacts with the WRN protein, and WRN recruits Pol? to the nucleolus . 29. Over-expression of nucleolar hPINX1 leads to increased TRF1 in the nucleolus and binding to telomeres. 30. Antibodies against the PAF49 protein can also be used as a marker for the nucleolus in immunofluorescence experiments.
