21. Oligodendrocytes evolution is similar to normal MS clinical courses22. Oligodendrocytes and Schwann cells have similar functions in the central and peripheral nervous system respectively.23. NG2 is another type of chondroitin sulfate proteoglycan that is expressed by oligodendrocyte precursor cells. 24. One peculiar expression pattern of CARKD is its differential expression through the development of oligodendrocytes . 25. This indicated that neuregulin is not necessary for the proliferation of oligodendrocyte multipotent precursor cells. 26. In contrast there were no apparent effects on the production of new astrocytes or oligodendrocytes . 27. The oligodendrocytes that originally formed a myelin sheath cannot completely rebuild a destroyed myelin sheath. 28. Chemotherapy can cause brain damage to the neural stem cells and oligodendrocyte cells that produce myelin. 29. Oligodendrocytes are found only in the central nervous system which comprises the brain and spinal cord.30. They are major constituents of oligodendrocytes .
