Evidence of retinal ganglion cell loss consistent with retrograde trans-synaptic degeneration has also been demonstrated in-vivo with optical coherence tomography in humans.
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To date, NASA has measured Optical Coherence Tomography ( OCT ) and A-scan axial length changes in the eye before and after spaceflight.
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MS patients show axonal loss in the retina and optic nerve, which can be measured by Optical coherence tomography or by Scanning laser polarimetry.
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Optical Coherence Tomography ( OCT ) is another NIR medical imaging technique capable of 3D imaging with high resolution on par with low-power microscopy.
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Joel Schuman, along with Eric Swanson, James Fujimoto, Carmen Puliafito, Charles Lin and David Huang, invented the optical coherence tomography ( OCT ) technology.
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Finally, high resolution spectral domain optical coherence tomography could prove to be a very promising and sensitive way of identifying optic neuritis in the future.
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Other important areas of research include the development of novel optical techniques for nano-optical measurements, diffractive optics, low-coherence interferometry, optical coherence tomography, and near-field microscopy.
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Other intravascular imaging techniques involving magnetic resonance imaging ( MRI ), optical coherence tomography ( OCT ), and near infrared spectroscopy are also being investigated.
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The device uses fractional flow reserve for measuring intra-arterial pressure and optical coherence tomography technology, which allows doctors to visually examine inside a patient's arteries.
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Applications demonstrated include optogenetic activation of focal cortical areas, " in vivo " imaging of cortical vasculature via fluorescence microscopy and 3D optical coherence tomography.
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