A "'paraganglioma "'is a rare metastases . " Paraganglioma " is now the most-widely accepted term for these lesions, that have been also described as : glomus tumor, chemodectoma, perithelioma, fibroangioma, and sympathetic nevi.
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Genetic testing should be considered with adrenocortical carcinoma; carcinoid tumors; diffuse gastric cancer; fallopian tube / primary peritoneal cancer; leiomyosarcoma; medullary thyroid cancer; paraganglioma / pheochromocytoma; renal cell carcinoma of chromophobe, hybrid oncocytic, or oncocytoma histology; sebaceous carcinoma; and sex cord tumors with annular tubules.
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Examples of autosomal dominant cancer syndromes are autoimmune lymphoproliferative syndrome ( Canale-Smith syndrome ), Beckwith Wiedemann syndrome ( although 85 % of cases are sporadic ), Birt Hogg Dub?syndrome, Carney syndrome, familial chordoma, Cowden syndrome, renal cell cancer ( HPRCC ), hereditary paraganglioma-pheochromocytoma syndrome, retinoblastoma, tuberous sclerosis, von Hippel-Lindau disease and Wilm's tumor.
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Accepted examples are piebaldism, Waardenburg syndrome, Hirschsprung disease, Ondine's curse ( congenital central hypoventilation syndrome ), pheochromocytoma, paraganglioma, Merkel cell carcinoma, multiple endocrine neoplasia, neurofibromatosis type I, CHARGE syndrome, familial dysautonomia, DiGeorge syndrome, Axenfeld-Rieger syndrome, Goldenhar syndrome ( a . k . a . hemifacial microsomia ), craniofrontonasal syndrome, congenital melanocytic nevus, melanoma, and certain congenital heart defects of the outflow tract, in particular.
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