21. He discovered hydrochloric acid in gastric juice and its chemical interaction with pepsin . 22. Hydrochloric acid activates this inactive form of enzyme into the active form, pepsin . 23. Gastric juice mainly contains hydrochloric acid and pepsin . 24. Pepsin is an aspartic protease, using a catalytic aspartate in its active site.25. Enzymes like pepsin are created in the form of pepsinogen, an inactive zymogen. 26. Pepsin may also cause mucosal damage during weakly acidic or non-acid gastric reflux.27. This team helps a lot of stores in Connecticut sell a lot of Pepsin and Zantac. 28. Pepsin breaks down proteins into polypeptides.29. The stability of pepsin at high pH has significant implications on disease attributed to laryngopharyngeal reflux. 30. Pepsin in airway specimens is considered to be a sensitive and specific marker for laryngopharyngeal reflux.