21. Despite concerns regarding its carcinogenicity, the use of phenolphthalein as a laxative is unlikely to cause ovarian cancer. 22. The FDA is also considering action on phenolphthalein and is expected to make a decision within the next few months. 23. All non-prescription laxatives that include phenolphthalein would have to be reformulated or taken off the market as part of 24. Phenolphthalein has been found to inhibit human cellular calcium influx via store-operated calcium entry ( SOCE, see ).25. The review of phenolphthalein ( cq ) was provoked by a government study that showed it to be carcinogenic in laboratory animals. 26. The ingredient, phenolphthalein , has been used in Ex-Lax for 91 years since the laxative was introduced in 1906. 27. At pH ranges outside 0-12, other molecular structure changes result in other color changes; see Phenolphthalein for details. 28. Other examples are phenolphthalein and thymolphthalein, colorless in acidic to neutral pH, but becoming pink and blue in alkaline environment. 29. Ex-Lax with phenolphthalein , a leader in the industry, has been sold in the U . S . since 1905. 30. If the sample contains hemoglobin, it will turn pink immediately upon addition of the peroxide, because of the generation of phenolphthalein .
