21. Melatonin is a hormone produced only at night by the pineal gland in the brain. 22. Papillary tumors characteristically show a discrete, compressive border with adjacent pineal gland and brain parenchyma. 23. In his perspective, the pineal gland is the place where all information " comes together ." 24. In 1649, Ren?Descartes studied the pineal gland . 25. Move the energy along the spine to the pineal gland in the centre of the brain. 26. The brain has a pineal gland , a feature formerly thought to be absent in the owls. 27. Nearly all vertebrate species possess a pineal gland . 28. Fibers enter the trigonum habenul?from the stalk of the pineal gland , and the habenular commissure. 29. It is most highly abundant in the pineal gland which is the site of melatonin synthesis. 30. In humans, neurotransmitters in the indolamine family are believed to be produced in the pineal gland .